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A Phase 2, Proof-of-Concept, Double-Blind-Randomized, Placebo-Controlled Adaptive Design Trial of Nicotinamide in MCI Due to AD and Mild AD Dementia

This research study seeks participants to evaluate if nicotinamide can reduce phosphorylation in subjects with mild cognitive impairment or mild...
Joshua Grill, PhD, and Aimee Pierce, MD

UCI campus (1100 Gottschalk Medical Plaza, Irvine; ICTS at Hewitt Hall, Irvine and Newport Diagnostic Center, Newport Beach); UCLA Center for Neurotherapeutics (UCLA Medical Center, 300 Medical Plaza, Westwood Blvd., Los Angeles).

A Phase 2, randomized, double-blind, placebo-controlled, dose-finding study to evaluate the safety, tolerability, and efficacy of KD025 in adult subjects with moderate to severe chronic plaque psoriasis who are candidates for systemic therapy or phototherapy

Natasha Mesinkovska, MD, PhD

At the UC Irvine campus:
Dermatology Clinical Research Center
843 Health Science Road
Hewitt Hall, Room 1001
Irvine, CA 92697

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A Phase 2b/3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study Investigating the Efficacy and Safety of JNJ-54861911 in Subjects Who Are Asymptomatic at Risk for Developing Alzheimer's Dementia

This research study seeks participants to study the efficacy and safety of JNJ-54861911 in those who are asymptomatic at risk for developing...
Aimee L. Pierce, MD

UCI campus (UCI MIND Gottschalk Medical Plaza, ICTS in Hewitt Hall Neuroscience Imaging Center in Irvine Hall) in Irvine

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects with Early Alzheimer's Disease

This research study seeks participants to study the efficacy and safety of aducanumab in subjects with early Alzheimer's disease.
Aimee Pierce, MD

UCI campus (UCI MIND Gottschalk Medical Plaza, ICTS in Hewitt Hall, Neuro Imaging Center), Newport Diagnostic Center