Rami N. Khayat, MD


Sleep Medicine, Pulmonary Disease, Critical Care Medicine

Clinical Interests

Sleep apnea, sleep disorders, Sleep disorders in patients with cardiac disease, Chronic respiratory failure and vent dependence, Critical care (shock, sepsis, respiratory failure, pneumonia)

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  • American Board of Internal Medicine, Critical Care Medicine [Internal Medicine]
  • American Board of Internal Medicine, Pulmonary Disease [Internal Medicine]
  • American Board of Internal Medicine, Sleep Medicine [Internal Medicine]
  • English
Medical School
University of Tishreen Faculty of Medicine
Medical College of Wisconsin Affiliated Hospitals IncInternal Medicine
University of Wisconsin HospitalPulmonary & Critical Care
University of Wisconsin HospitalSleep Medicine
Professional Positions
  • Professor — Department of Psychiatry & Human Behavior, UCI School of Medicine
  • Professor — Division of Pulmonary and Critical Care Medicine, Department of Medicine, UCI School of Medicine
  • Medical Director — UCI Health Sleep Disorders Center
  • Director — Pulmonary & Critical Care Fellowship Program
More Information

Dr. Rami N. Khayat is a nationally recognized expert in sleep-disordered breathing who is affiliated with the UCI Health Sleep Medicine and Pulmonary Medicine and Critical Care services.

His research addresses the mechanism of cardiovascular disease in sleep apnea and the impact of sleep disorders on the outcomes of patients with heart failure.

Khayat earned his medical degree from Tishreen University in Syria. He completed an internal medicine residency at the Medical College of Wisconsin in Milwaukee, followed by a pulmonary-and-critical-care fellowship and a sleep-medicine fellowship from the University of Wisconsin in Madison.

Khayat has received several grants from the National Institutes of Health (NIH) and medical device companies. He frequently serves on review panels for the NIH, the Department of Veterans Affairs and industry. He currently is one of the leaders of an NIH-funded multicenter clinical trial evaluating the impact of low-flow oxygen on patients with heart failure and central sleep apnea.

Khayat, who comes to UCI from Ohio State University Wexner Medical Center in Columbus, is the author or co-author of numerous peer-reviewed publications. 

He sees patients at UCI Medical Center in Orange and UCI Health Newport — Birch Street.

Neuropsychiatric Center
101 The City Drive South, Building 3
Orange, CA 92868
Phone: 714-456-5902
Fax: 714-456-5112
UCI Health Newport — Birch Street
20350 SW Birch St.
Newport Beach, CA 92660
Phone: 714-456-5902
Fax: 949-250-9177