Dr. Kenneth Chang is a board-certified UCI Health interventional gastroenterologist and executive director of the UCI Health Digestive Health Institute.

Kenneth J. Chang, MD



Clinical Interests

Barrett's esophagus, interventional endoscopy, endoscopic ultrasound (EUS), gastroesophageal reflux disease (GERD), gastrointestinal oncology: pancreatic & esophageal cancer

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  • American Board of Internal Medicine, Gastroenterology
  • American Board of Internal Medicine, Internal Medicine
  • English
  • Chinese
Medical School
Brown University Program in Medicine
Rhode Island HospitalInternal Medicine
Rhode Island HospitalInternal Medicine
UC Irvine Medical CenterGastroenterology & Hepatology
Professional Positions
  • Professor and Chief — Division of Gastroenterology & Hepatology, Department of Medicine, UCI School of Medicine
  • Executive Director — UCI Health Digestive Health Institute
  • Vincent Kong Endowed Chair — Gastrointestinal Endoscopic Oncology
Awards and Recognition
  • America's Top Doctors (Barrett's Esophagus, Endoscopic Ultrasound, Gastrointestinal Cancer, Interventional Endoscopy, Pancreatic Cancer), Castle Connolly Medical Ltd., 2012
  • Best Doctors in America® — Gastroenterology, 2008-2016
  • Physicians of Excellence, Orange County Medical Association — 2012-2023
  • Excellence in Teaching Award — Division of Gastroenterology and Hepatology, Department of Medicine, UCI School of Medicine
More Information

Dr. Kenneth Chang is a board-certified UCI Health gastroenterologist who specializes in interventional endoscopy for esophageal and gastrointestinal disorders. He is also the executive director of the UCI Health Digestive Health Institute.

He is an expert in endoscopic ultrasound (EUS), EUS-guided fine needle aspiration, EUS-guided intervention and endoscopic retrograde cholangiopancreatography. He is also skilled in the endoscopic treatment of gastroesophageal reflux disease, endoscopic mucosal resection, laser-induced endomicroscopy, optical coherence tomography, radiofrequency and cryoablation therapy for Barrett’s esophagus and esophageal cancer.

Chang’s clinical research focuses on development of endoscopic modalities for cancer diagnosis, staging and therapy. He has pioneered the development of EUS-guided fine-needle aspiration and EUS-guided fine-needle injection. He is the author of more than 200 publications and book chapters regarding the technique’s use in gastrointestinal malignancies. He has conducted numerous clinical trials on the development of new biologic agents against esophageal and pancreatic cancers.

Chang completed his medical degree and residency at Brown University in Providence, R.I. He then finished a fellowship in gastroenterology at UCI Medical Center and the UCI School of Medicine, where he has been a faculty member for more than 25 years. He holds the Vincent Kong Chair of Gastrointestinal Oncology and serves as chief of the medical school's Division of Gastroenterology and Hepatology.

Academic Profile

View this doctor's faculty profile ›

Speakers Bureau Topics

  • Endoscopic Therapy for GERD
  • Endoscopic Ultrasound
  • Endoscopic Therapy for Barrett’s Esophagus
  • Esophageal Cancer
  • Gastrointestinal Oncology
  • Pancreatic Cancer
  • Photodynamic Therapy

UCI Health Chao Family Comprehensive Digestive Disease Center
101 The City Drive South, Building 22C
Orange, CA 92868