Therapeutic effects of exercise in adults with amnestic mild cognitive impairment

July 07, 2016
HS 2016-2938
Cognitive impairment, Memory disorders, Alzheimer’s, Dementia, Memory loss
Aimee Pierce, MD
UC Irvine campus (at UCI MIND at Gottschalk Medical Plaza and the Institute for Clinical and Translational Science in Hewitt Hall); the Newport Diagnostic Center, the Newport-Mesa YMCA and the Huntington Beach Family YMCA

To evaluate whether 18 months of moderate to high intensity exercise will improve cognition in older adults with mild cognitive impairment (MCI).

Adult participants from 65 to 89 years of age who have been diagnosed with MCI

You will be asked to complete a total of seven (7) clinic visits over the course of the study and participate in a structured exercise program four (4) days a week for 18 months. The total time commitment is 20 months.

You will receive an 18-month membership to a YMCA. Participating in the exercise program may or may not improve your condition.

Information collected from this study may increase knowledge regarding the treatment of Alzheimer’s disease and help people in the future.

You are eligible to receive the following compensation in cash during the course of this study:

  • $100 for each completed MRI scan; there are two (2) MRI scans ($200 maximum)
  • $75 for each completed lumbar puncture (optional) ($150 maximum)
  • $75 for completing the baseline clinical visit; $50 for completing the clinical visit in month 12, and $25 for completing the clinical visit in month 18 ($150 maximum)

Total compensation for this study is a maximum of $500 in cash.

Participants will not be reimbursed for travel-related expenses.

Exercise therapy
Beatriz Yanez, RN, clinical research nurse and coordinator