Mark E. Mapstone, PhD


Clinical Neuropsychology

Clinical Interests

Alzheimer's disease, cognitive assessment of older adults, cognitive disorders, dementia and brain aging, memory loss and dementia

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Medical Services
  • English
University of Rochester Medical CenterClinical Neuropsychology
Professional Positions
  • Professor and Chief — Neuropsychology Division, Department of Neurology, UCI School of Medicine
  • Co-director — Center for Aging Research in Down Syndrome, UCI School of Medicine
  • Professor — Institute for Memory Impairments and Neurological Disorders (UCI MIND)
  • Fellow — Center for the Neurobiology of Learning and Memory
More Information

Mark E. Mapstone, PhD, is a licensed UCI Health clinical neuropsychologist who specializes in cognitive assessments of older adults. He has a special interest in developing strategies to maintain successful cognitive aging.

A professor of neurology in the UCI School of Medicine, Mapstone has long conducted research on the early detection of neurological disease using cognitive tests and biomarkers obtained from blood.

Mapstone earned a doctorate in clinical psychology at Northwestern University in Chicago, Ill. He completed fellowship training in neuropsychology and experimental therapeutics at the University of Rochester in Rochester, N.Y. The National Institute on Aging presented him with a Career Development Award and his research has been funded by the National Institutes of Health.

The author of more than 100 research articles and book chapters, Mapstone and fellow UCI School of Medicine researchers are spearheading an international effort to identify biomarkers of Alzheimer’s disease with a $109 million grant from the National Institutes of Health.

Mapstone sees patients in Irvine and Newport Beach

UCI Health Gottschalk Medical Plaza
1 Medical Plaza Drive
Irvine, CA 92697
Phone: 949-824-8600
Fax: 855-209-8413
UCI Health Newport — Old Newport Boulevard
401 Old Newport Blvd., Suite 201
Newport Beach, CA 92663