UCI Health will see you now: Welcome to our new co-workers and patients from Fountain Valley, Lakewood, Los Alamitos and Placentia Linda! 

Dr. Jason Samarasena is a board-certified UCI Health gastroenterologist

Jason B. Samarasena, MD



Clinical Interests

cholangiopancreatography, colon cancer screening, confocal laser endomicroscopy, endoscopic mucosal resection of large polyps, gastric intestinal metaplasia, GERD and Barrett's esophagus, interventional endoscopic ultrasound, interventional endoscopy

Nickname: Dr. Sam
MyChart patient portal offers a convenient and secure way to manage your healthcare online. Use MyChart to schedule appointments, request prescription renewals, send messages to your care team and more.
  • American Board of Internal Medicine, Gastroenterology [Internal Medicine]
  • English
Medical School
Memorial University of NewfoundlandM.D.
University of California Irvine, Medical CenterInternal Medicine
University of California Irvine, Medical CenterGastroenterology
Professional Positions
  • Director — Advanced Endoscopic Imaging, Chao Family Comprehensive Digestive Disease Center 
  • Associate Professor — Division of Gastroenterology & Hepatology, Department of Medicine, UC Irvine School of Medicine
Awards and Recognition
  • Best Doctors in America® — Gastroenterology, 2015, 2016
  • Physicians of Excellence, Orange County Medical Association — 2020-2023
More Information

Dr. Jason Samarasena is a UCI Health physician who specializes in treating gastrointestinal disorders, including gastroesophageal reflux disease, esophageal disease, pancreatic cysts, biliary tract disorders, gastric intestinal metaplasia and colorectal cancer.

His research interests include advanced endoscopic imaging, characterization and treatment of pancreatic cysts, confocal laser endomicroscopy, bowel preparation before colonoscopy, endoscopic mucosal resection and endoscopic submucosal dissection.

Samarasena received his medical degree from Memorial University of Newfoundland, Canada, where he graduated on the Dean’s List. He completed both general gastroenterology and interventional endoscopy fellowships at UC Irvine. 

Press Ganey has named Samarasena as one of the top five physicians for patient satisfaction in the ambulatory surgery group at UCI Health. He was named the 2016 Teaching Attending of the Year by the UC Irvine Gastroenterology Fellowship. He is the current president of the Orange County GI Society.

Speakers Bureau Topics

  • Advanced Endoscopic Imaging: Confocal Laser Endomicroscopy
  • Barrett's Esophagus
  • Colon Cancer Screening
  • Colonoscopy
  • Colonoscopy: Bowel Preparation
  • Diseases of the Gallbladder and Biliary System
  • Diseases of the Pancreas
  • Endoscopic Ultrasound
  • Esophagogastroduodenoscopy (EGD)
  • Gastroenterology Topics, Interventional/Advanced Endoscopy
  • GERD
  • Pancreatic Cysts
  • Small Bowel Enteroscopy

UCI Health Chao Family Comprehensive Digestive Disease Center
101 The City Drive South, Building 22C
Orange, CA 92868
Fax: 855-813-0240