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Claire Henchcliffe, MD, DPhil


Movement Disorders, Neurology

Clinical Interests

Parkinson's disease, tremor, cognitive dysfunction in movement disorders

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  • American Board of Psychiatry and Neurology, Neurology
  • English
Medical School
Columbia University College of Physicians and SurgeonsMedicine
New York Presbyterian Hospital/Columbia University Medical CenterMedicine
New York Presbyterian Hospital/Columbia University Medical CenterNeurology
Columbia University Medical CenterMovement Disorders
Grad School
University of Oxford — doctorate in Philosophy
University of Cambridge-UC Berkeley — postdoctoral fellowship in Genetics
Professional Positions
  • Professor and Chair — Department of Neurology, UCI School of Medicine 
  • Fellow — American Neurological Association
  • Fellow — American Academy of Neurology
Awards and Recognition
  • Gibbs Prize in Biochemistry, University of Oxford — 1985
  • Dee Scholarship for Academic Achievement, University of Oxford — 1985-1988
  • Alpha Omega Alpha Honor Medical Society — 1997
  • Helen M. Sciarra Prize in Neurology — 1997
  • Daisy and Paul Soros Clinical Scholar in Neurology — 2006-2012
  • International Association of Healthcare Professionals (IAHCP) Top Neurologist in New York, NY/Leading Physicians of the World — 2011-2018
  • The Best Doctors in America® — 2013-2015
More Information

Dr. Claire Henchcliffe is a board-certified UCI Health neurologist who specializes in the diagnosis and treatment of movement disorders. She has more than 20 years of experience treating patients with Parkinson’s disease and related conditions.

She earned her medical degree at the College of Physicians and Surgeons of Columbia University in New York City. She completed an internal medicine internship and neurology residency at New York Presbyterian Hospital/Columbia University Medical Center, followed by a movement disorders fellowship at Columbia University Medical Center.

She previously earned a doctorate in philosophy from the University of Oxford in the United Kingdom and completed a postdoctoral fellowship in genetics at the University of Cambridge and UC Berkeley.

Prior to becoming chair of the UCI School of Medicine's Department of Neurology, Henchcliffe served as Weill Cornell Medicine's vice-chair for clinical neurology research and chief of neurodegenerative disorders, and as the attending neurologist at New York Presbyterian Hospital, both in New York City.

An internationally recognized clinician and scientist in neurological disorders, Henchcliffe's research is focused on developing new treatments for Parkinson’s disease, including stem cell-based regenerative therapy and gene therapy. At Weill Cornell Medicine, she led a clinical trials network team as part of the National Institute of Neurological Disorders and Stroke (NINDS) initiative to improve treatment for neurological diseases in partnership with academia, private foundations and industry.

She has published in many peer-reviewed journals and has made presentations at national and international conferences on Parkinson’s disease and, most recently, on stem-cell therapies and biomarker development.

Henchcliffe sees patients at UCI Health Gottschalk Medical Plaza in Irvine and the UCI Health Susan Samueli Integrative Health Institute, also in Irvine.

UCI Health Gottschalk Medical Plaza
1 Medical Plaza Drive
Irvine, CA 92697
Phone: 949-824-8600
Fax: 855-209-8413
UCI Health Susan Samueli Integrative Health Institute
856 Health Sciences Road
Suite 2600
Irvine, CA 92617
Phone: 949-824-7000