UCI Health will see you now: Welcome to our new co-workers and patients from Fountain Valley, Lakewood, Los Alamitos and Placentia-Linda!
Read more about our recent acquisition.

Frank P.K Hsu

Frank P. Hsu, MD, PhD


Neurological Surgery

Clinical Interests

aneurysms, arteriovenous malformations, deep brain stimulation, functional neurosurgery for movement disorders (Parkinson's, essential tremor, dystonia), malignant and benign tumors of the brain and spine, pituitary tumors, radiosurgery, trigeminal neuralgia

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  • American Board of Neurological Surgery, Neurological Surgery
  • English
  • Chinese
  • Taiwanese
Medical School
University of Maryland
Oregon Health Sciences UniversityGeneral Surgery
Oregon Health Sciences UniversityNeurological Surgery
Barrow Neurological InstituteCerebrovascular & Skull Base Surgery
Oregon Health Sciences UniversityFunctional Stereotactic & Pain Surgery
Grad School
University of Maryland — PhD, Mechanical Engineering
Professional Positions
  • Professor and Chair — Department of Neurological Surgery, UCI School of Medicine
  • Director — UCI Health Neurosurgery Services
  • Professor — Department of Biological Engineering, UCI Henry Samueli School of Engineering
  • Professor — Department of Otolaryngology /Head and Neck Surgery, UCI School of Medicine

Awards and Recognition
  • Physicians of Excellence, Orange County Medical Association — 2018-2024
  • Best Doctors in America® — Neurological Surgery — 2015-2016

More Information

Dr. Frank P.K. Hsu is a fellowship-trained neurosurgeon who specializes in cerebrovascular, minimally invasive and open skull base surgery. He has extensive expertise in radiosurgery and functional surgery for movement disorders, deep brain stimulation, epilepsy and pain.

He also is highly skilled at treating patients with aneurysms, arteriovenous malformations and cavernous malformations, as well as malignant and benign tumors of the brain and spine, including pituitary tumors and meningiomas.

Hsu received his medical degree from the University of Maryland in Bethesda, where he previously earned a PhD in mechanical engineering. He completed an internship in general surgery and a residency in neurological surgery at Oregon Health Sciences University in Portland. He completed fellowship training in cerebrovascular and skull base surgery at the Barrow Neurological Institute in Phoenix, Ariz. He returned to Oregon Health Sciences University for fellowship training in functional stereotactic and pain surgery.

His research interests are in the biomechanics of cerebral aneurysms, functional neurosurgery and epilepsy.

Before coming to UCI Medical Center, he served as director of functional, cerebrovascular and skull base surgery at Loma Linda University Medical Center in Loma Linda, Calif..

Hsu, who also speaks Mandarin and Taiwanese, sees patients in Orange and Costa Mesa

UCI Health Neurosurgery Services
101 The City Drive South, Pavilion 1
Building 30
Orange, CA 92868
Phone: 714-456-6966
Fax: 855-209-8413
UCI Health — Costa Mesa
1640 Newport Blvd.
Costa Mesa, CA 92627
Phone: 949-456-6966
Fax: 844-965-9446