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Looking for a clinical trial that's right for you?

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UCI Health, your source for clinical trials

UCI Health has one of Orange County’s largest clinical trials programs, with 1,000-plus trials and 3,450 patients enrolled in the past year. By participating in a clinical trial, you help shape the future of medicine. Help us discover and cure!

UCI Clinical Trials

Partnered with our leading academic medical center, we offer top-tier care and access to leading-edge trials from across the nation. We are dedicated to serving patients, researchers and sponsors with unwavering commitment and excellence.

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What are clinical trials?

Clinical trials evaluate the effects of new interventions on health.
Learn more about clinical trials
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Why participate?

Discovery depends on you!
Learn more about why to participate in a clinical trial
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Get involved!

Become a partner in discovering new clinical therapies. 
Get involved with Clinical Trials

Featured Trials

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Phase 3 Study to Evaluate Remibrutinib in Patients with Generalized Myasthenia Gravis

A randomized, double-blind, placebo-controlled Phase 3 study to evaluate the efficacy, safety, and tolerability of Remibrutinib in patients with generalized myasthenia gravis, followed by an open label extension phase.
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A Phase 3 Study of Telitacicept in Patients with Generalized Myasthenia Gravis

A multicenter, randomized, double-blind, placebo-controlled Phase 3 Trial to evaluate efficacy and safety of Telitacicept in patients with generalized Myasthenia Gravis.
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researchers taking a samples from a test tube

A study to evaluate the efficacy and safety of JCELL in patients with retinitis

The primary objective of this Phase 2/3 study is to evaluate the efficacy, safety and tolerability of a single intravitreal injection of jCell (famzeretcel) for the Treatment of Retinitis Pigmentosa (RP).
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doctor going over test results with patient

A Phase 1 Study of FT819 in Participants with Moderate to Severe Active Systemic Lupus Erythematosus.

This is a Phase 1 study designed to evaluate the safety, pharmacokinetics (PK), and anti-B-cell activity of FT819 following treatment with or without auxiliary medicinal product (AMP) in participants with moderate to severe active systemic lupus erythematosus (SLE). The study will consist of a dose-escalation stage, followed by an expansion stage to further evaluate the safety and activity of FT819.
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Lung Cancer Screening of Family Members of Patients with Mutation-Driven Lung Cancer

The purpose of this research study is to find out whether researchers can help find lung cancer early by screening immediate family members of patients with lung cancer who have a genetic mutation by undergoing a low dose computed tomography (CT) scan.
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Repurposing Riluzole for Cancer-Related Cognitive Impairment: a Pilot Trial

A phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining the impact of Riluzole therapy on circulating brain derived neuropathic factor (BDNF) levels of breast cancer survivors with cancer related cognitive impairment.
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GLP-1 Drugs

In this episode, UCI Health experts Dr. Qin (Kin) Yang, Dr. Andy Lee, and Professor Nathan Wong discuss GLP-1 medications like Ozempic, Wegovy, Mounjaro, and Zepbound—exploring their benefits for weight loss, diabetes, and heart disease, as well as the broader cost and access implications. 

 

View the transcript of this audio-only podcast.

Live Well with UCI Health on iHeart Radio: GLP-1 discussion with Dr. Qin Yang, Dr. Andy Lee and Professor Nathan Wong

Advancing Spine Care

Advancing Spine Care

Learn more about clinical trials at UCI Health

Explore valuable resources and support for all aspects of clinical trials at UCI health

Find a Trial
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For Participants For Sponsors For Prinicipal Investigators For Referring Clinicians

UCI Research News

This illustration shows the HyperQure™ laparorscopic device wrapped around a kidney artery and applying heat to destroy the renal nerves. Increased activity of the renal nerves, pictured as white lines on the artery's outer wall, is linked to uncontrolled hypertension.

First U.S. test of nerve-blocking device for resistant hypertension

UCI Health urologist Dr. Pengbo Jiang recently performed the first U.S. procedure using radiofrequency electrodes to block nerves surrounding the renal arteries without damaging the blood vessel’s integrity.
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Lung Cancer Screening

Lung cancer screening is essential for early detection, treatment

When lung cancer is diagnosed early, surgery can offer a cure. Other treatment options available include immunotherapy, targeted therapy and radiation.
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Advancing regenerative medicine therapies

University and community guests recently gathered to celebrate the 7,700 square-foot Good Manufacturing Practice facility’s grand opening in Hewitt Hall’s basement on the UC Irvine campus.
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