UCI Health will see you now: Welcome to our new co-workers and patients from Fountain Valley, Lakewood, Los Alamitos and Placentia Linda! 

Dr. Rami N. Khayat is board-certified UCI Health specialist in pulmonary and critical care medicine as well as sleep breathing disorders.

Rami N. Khayat, MD


Critical Care Medicine, Pulmonary Disease, Sleep Medicine

Clinical Interests

sleep apnea, sleep disorders, sleep disorders in patients with cardiac disease, chronic respiratory failure and vent dependence, critical care (shock), sepsis, respiratory failure, pneumonia)

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  • American Board of Internal Medicine, Critical Care Medicine [Internal Medicine]
  • American Board of Internal Medicine, Pulmonary Disease [Internal Medicine]
  • American Board of Internal Medicine, Sleep Medicine [Internal Medicine]
  • English
Medical School
University of Tishreen Faculty of Medicine
Medical College of Wisconsin Affiliated Hospitals IncInternal Medicine
University of Wisconsin HospitalSleep Medicine
University of Wisconsin HospitalPulmonary & Critical Care
Professional Positions
  • Professor — Division of Pulmonary & Critical Care Medicine, Department of Medicine, UCI School of Medicine
  • Professor — Department of Psychiatry & Human Behavior, UCI School of Medicine
  • Medical Director — UCI Health Sleep Medicine Services
  • Director — Pulmonary & Critical Care Fellowship Program
More Information

Dr. Rami N. Khayat is a board-certified UCI Health pulmonologist and sleep-medicine specialist who is a nationally recognized expert in sleep-disordered breathing. He serves as medical director of UCI Health Sleep Medicine Services.

Khayat earned his medical degree from Tishreen University in Syria. He completed an internal medicine residency at the Medical College of Wisconsin in Milwaukee, followed by a pulmonary-and-critical-care fellowship and a sleep-medicine fellowship at the University of Wisconsin School of Medicine and Public Health in Madison.

His research addresses the mechanism of cardiovascular disease in sleep apnea and the impact of sleep disorders on the outcomes of patients with heart failure. He is the author or co-author of many peer-reviewed publications and has received several grants from the National Institutes of Health (NIH) and medical device companies. He has frequently served on review panels for the NIH, the Department of Veterans Affairs and industry. He is currently a leader for an NIH-funded multicenter clinical trial to evaluate the impact of low-flow oxygen on patients with heart failure and central sleep apnea. 

Khayat sees patients in Orange and Newport Beach.

UCI Health Neuropsychiatric Center
3800 W. Chapman Ave., Suite 500
Orange, CA 92868
Phone: 714-456-5902
Fax: 714-456-5112
UCI Health Newport — Birch Street
20350 SW Birch St.
Newport Beach, CA 92660
Phone: 714-509-2230
Fax: 949-250-9177