Oncocytic carcinomas, also known as Hürthle cell carcinomas, are a rare subtype of well-differentiated thyroid carcinoma, accounting for approximately 3 percent of thyroid carcinomas. They are more aggressive and more likely to metastasize than other types of well-differentiated thyroid carcinoma.
Like follicular cell carcinoma, the diagnosis of a Hürthle cell carcinoma requires an open biopsy because on fine needle aspiration, Hürthle cell tumors can be benign Hürthle cell adenomas or Hürthle Cell carcinoma.
If a Hürthle cell carcinoma is found on open biopsy, the treatment for Hürthle cell carcinoma is a total thyroidectomy followed by radioactive iodine treatment.
However, Hürthle cell carcinomas are less sensitive to radioactive iodine therapy than other types of well-differentiated carcinoma.
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