Neurogenetics Program
Neurogenetics is a field of study that aims to determine genetic causes of nerve and brain disorders, including neurodegenerative disease, epilepsy, movement disorders, neuromuscular conditions and leukodystrophies. Using recent advances in genome sequencing, neurogenetics works to pinpoint genetic causes of inherited diseases.
The neurogenetics team at UCI Health provides a personalized approach to each patient who has been diagnosed with a genetic neurological disorder — as well as diagnoses and treats potentially at-risk family members — to help improve quality of life.
For more information or to schedule an appointment, please call:
- 949-824-8600 for the Gottschalk Medical Plaza in Irvine
- 714-456-7720 for the Pavilion 1 clinic in Orange
Why choose us
The UCI Health neurogenetics team diagnoses and treats rare genetic neurological disorders and neurometabolic conditions. Our team offers genetic counseling and testing for patients who do not have a diagnosis and carefully interpret results to develop a personalized treatment plan, not just for patients, but also their families who may wonder if they have an inherited disease.
- Ataxia
- Autism
- Familial or early-onset dementia
- Dystonia
- Familial or childhood onset epilepsy
- Inborn errors of metabolism
- Leukodystrophies
- Lysosomal storage diseases
- Muscular dystrophy
- Neurofibromatosis
- Neurometabolic disorders
- Hereditary neuropathy
- Neurotransmitter disorders
- Familial or early-onset Parkinson’s disease
- Young onset strokes
- Other rare neurogenetic conditions
Neurogenetics at UCI Health treats both children and adults. To improve care, our expert physicians conduct research to provide effective therapies for the various neurological disorders.
In addition to the neurogenetics clinic, UCI Health also has programs dedicated to Huntington’s disease, ALS and ataxia. We also work closely with the Children’s Hospital of Orange Country (CHOC) to treat both children and adults with neurometabolic disorders.
Our team
Dr. Changrui Xiao, a board-certified neurologist, clinical geneticist and medical biochemical geneticist, spearheads the neurogenetics program at UCI Health. His clinical interests include inborn errors of metabolism, hereditary neurological disorders and lysosomal storage disorders.
UCI Health neurologists are national leaders in caring for patients suffering from various neurological disorders and pursue leading-edge research to advance care for these diseases and conditions. Our patients often have access to new therapies and treatments before they are available elsewhere.
In addition to Xiao, our team includes:
