Hereditary and High-Risk GI Cancer Prevention Clinic

If you or your loved ones have a personal or family history of gastrointestinal (GI) cancers, the UCI Health Hereditary and High-Risk GI Cancer Prevention Clinic is here to support you. 

We specialize diagnosis and care for individuals at increased genetic risk, helping you take control of your health with compassionate guidance, early detection and evidence-based prevention. 

Our approach to hereditary and high-risk GI cancer prevention and treatment

Personalized care, every step of the way

Our dedicated team brings together experts in genetics, gastroenterology, oncology and surgery to offer a full range of personalized services. Our path to care is built to catch what routine screening can miss.

Comprehensive genetic risk assessment

Genetic, personal and family history are flagged early through referral or other screening tools. Our licensed genetic counselors take time to understand your family history and coordinate appropriate testing. This will help you make informed choices about your health. 

Tailored screening and prevention strategies

Based on your risk profile, we design a plan just for you. The plan may include advanced colonoscopy and endoscopy screenings, imaging, biomarker testing, chemoprevention or preventive surgery. 

Seamless, coordinated care

We collaborate with specialists across disciplines to ensure you receive thorough and unified care at every stage.

Access to leading-edge research

As part of Orange County's only academic health system, we offer groundbreaking clinical trials focused on hereditary GI cancers. Participation may provide access to therapies before they are widely available. 

Hereditary GI conditions we treat

Our clinic is a trusted resource for individuals and families facing increased risk of: 

• Colorectal cancer
• Gastric (stomach) cancer
• Pancreatic cancer
• Other hereditary GI cancers

We also evaluate and support those with known hereditary cancer syndromes, such as Lynch syndrome and familial adenomatous polyposis (FAP), or known genetic mutations linked to increased cancer risk. 

What to expect

From the moment you interact with our clinic, you receive a thorough assessment. 

We learn about the reason for your referral and your personal cancer history. We note any history of colon polyps and upper GI tract findings. We review your personal family genetic testing results, then we account for any lifestyle factors, current symptoms and goals for your visit. 

You'll leave with a personalized prevention plan, whether that includes scheduling regular colonoscopies, upper endoscopies or other monitoring, making lifestyle changes and performing family testing.