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UCI Health Sarcoidosis Integrated Care and Research Program

The UCI Health Sarcoidosis Integrated Care and Research Program is a multi-disciplinary team of clinicians with expertise in the diagnosis and management of individuals affected by sarcoidosis.

Sarcoidosis is a multi-system disease, and as such, providers of various disciplines are required for optimal patient care. Our team is dedicated to both excellence in patient care and research. We continuously strive to better understand the pathophysiology of sarcoidosis, contribute to the development and optimization of available treatments, andwork together as a team to provide seamless multi-disciplinary care.

We are proudly an institutional member of the Foundation for Sarcoidosis Research’s Global Clinic Alliance program.

Research

Manzano GS, Eaton J, Levy M, et al. Consensus Recommendations for the Management of Neurosarcoidosis: A Delphi Survey of Experts Across the United States. Neurol Clin Pract. 2025 Apr;15(2):e200429. doi: 10.1212/CPJ.0000000000200429. Epub 2025 Jan 15. PMID: 39830676; PMCID: PMC11737638. https://pmc.ncbi.nlm.nih.gov/articles/PMC11737638/pdf/CPJ-2024-100226.pdf

Manzano GS, Balaban D, Zhang Y, et al. A Multi-Center Retrospective Cohort Study of Neurosarcoidosis Myelitis: Current Observations and Future Directions. Ann Clin Transl Neurol. 2025 Dec;12(12):2589-2599. doi: 10.1002/acn3.70200. Epub 2025 Sep 17. PMID: 40963302; PMCID: PMC12698951. https://pmc.ncbi.nlm.nih.gov/articles/PMC12698951/pdf/ACN3-12-2589.pdf

Webb LM, Chen JJ, Aksamit AJ, Bhattacharyya S, Chwalisz BK, Balaban D, Manzano GS, Ali AS, Lord J, Clardy SL, Samudralwar RD, Mao-Draayer Y, Garrity JA, Bhatti MT, Turner LE, Flanagan EP. A multi-center case series of sarcoid optic neuropathy. J Neurol Sci. 2021 Jan 15;420:117282. doi: 10.1016/j.jns.2020.117282. Epub 2020 Dec 19. PMID: 33358503. https://www.jns-journal.com/article/S0022-510X(20)30618-3/fulltext

Podcast on neurosarcoidosis and rare neuro-immune disorders

Sarcoidosis Integrated Care and Research team

Dr. Giovanna Manzano
Giovanna S. Manzano, MD, MSc
Neuroimmunologist, Director of the UCI Health Sarcoidosis Integrated Care and Research Program
Dr. Anastasia Chumakova
Anastasia Chumakova, MA
Neuro-immunologist
Dr. Olivia Lee
Olivia L. Lee, MD
Ophthalmologist
Rodney Mardirosian
Rodney Mardirosian, MPH
UCI Health Sarcoidosis Program Clinical Patient Liaison
Dr. Tahseen Mozaffar
Tahseen Mozaffar, MD
Neuromuscular Specialist
Dr. Amin Sabet
Amin Sabet, MD, FACC
Cardiologist, Director of UCI Cardio-Rheumatology Program
Dr. Samuel Spiegel
Samuel Spiegel, MD
Neuro-ophthalmologist